Automatic dysfunction after abdominal surgery and the role of non-invasive vagus nerve stimulation

A2003067

Dr. Stephen Chapman and his team at the University of Leeds are exploring innovative ways to improve recovery after abdominal surgery, a procedure that often leads to complications such as infections, heart attacks, and slow bowel function. Around 4 in every 10 people will experience a complication which can significantly impact recovery times. The team believes that stimulating the vagus nerve, part of the body's "fight or flight" system, could enhance recovery. This nerve can be stimulated using a simple electrical device attached to the ear, which has previously been used safely to improve other health conditions, including heart issues.In this study, patients scheduled for bowel surgery will be invited to participate. The team will evaluate the effectiveness of the device and whether it works consistently across different individuals. They are particularly focused on whether it can improve bowel function post-surgery. If the results are promising, the research will be expanded into a larger study, potentially benefiting thousands of patients undergoing surgery each year. This research aims to provide better recovery outcomes and reduce the incidence of post-surgical complications. 

Lead Researcher	Dr Stephen Chapman Uni of Leeds, NIHR Clinical Lecturer, General Surgery Registrar
Co-Researchers	Dr Beatrice Bretherton-Liu (EC) Prof David Jayne Dr Sheila Black
Host Organisation	Abdominal Medicine & Surgery Leeds Teaching Hospitals Trust
Grant Amount	£9,956
Start Date	01/01/2025
Estimated Duration	14 months
Impact Areas	Innovation & Health Technologies
Tags/key notes	Early Career Researcher Oral and gastrointestinal