Improving the quality of transplant livers for cancer patients

A2003267

Hepatocellular carcinoma (HCC, a primary liver cancer) is becoming an increasingly common reason for patients to need a liver transplant. However, approximately 15% of patients will experience recurrence of the cancer after transplant. One potential way to reduce this recurrence is to improve the quality of the liver graft.

HOPE (hypothermic oxygenated perfusion) is a process of delivering oxygen and nutrients to donor livers before they are transplanted, to improve the quality of the liver. The aim of this study is to show that post-transplant outcomes improve when HOPE is used compared to standard static cold storage organ preservation. 

Lead Researcher	Dr Barbara Fiore Consultant Surgeon
Host Organisation	Leeds Teaching Hospitals NHS Trust
Grant Amount	£3,700.00
Start Date	01/01/2025
Estimated Duration	36 months
Impact Areas	Health Inequalities - Cancer Care
Tags/key notes	Cancer and neoplasms